Antiseptic or medicated dressing or material and the manufacture thereof



Dec. 8, 1936. zlSSERMAN r 2,063,218 I ANTISEPTIC'OR MEDICATED DRESSING OR MATERIAL AND THE MANUFACTURE THEREOF Filed Aug. 22, 1933 ma Maw,

Patented Dec. 8, 1936 UNITED STATES ANTISEPTIC OR MEDICATED DRESSING 0R MATE RIAL AND THE MANUFACTURE THEREOF Leon Zisserman and Edward Shore, London, England Application August 22, 1933, Serial No. 686,308

In G

2 Claims.

This invention relates to antiseptic or medicated dressings or other materials and the manufacture thereof and it has for its object to render such dressings or materials sterile and to impart to the same the further property of inhibition whereby the growth of any micro-organism implanted upon it subsequent to sterilization is killed or inhibited.

As the result of numerous laboratory experiments and practical tests we have discovered that the above object may be fulfilled by treating a dressing or material with sodium-bore fluoride more commonly known as fiuoborate of sodium (NaBF4) whereby the same is caused to contain such substance in quantity suflicient to give to the dressing or material the desired properties of sterility and inhibition.

Broadly therefore the present invention consists of a dressing or material which contains fiuoborate of sodium (sodium-boro fluoride) sumcient to render the same sterile and lethal and/or inhibitory to the growth of micro-organisms.

The fiuoborate of sodium being readily soluble may be introduced into the dressing or material by a process of impregnation by immersing the dressing or material in or spraying the same with a solution of the salt' but it is to be understood that the invention may be carried into effect by other suitable methods of treatment, if

any.

Before arriving at the minimum strength of the solution of the salt necessary to impart the desired properties of the dressings or materials it was first necessary to conduct experiments to ascertain the variations in the lethal and/ or inhibitory strength of the salt 'when in solution in'wa-ter, broth, serum, blood and urine and when used with the various materials employed in the manufacture of dressings. The relative amounts of the above fluids the materials would individually absorb as dressings had also to be determined.

In these experiments impregnation of the materials was eflected by means of both immersion and by a spraying process, excess moisture being removed and even distribution of the salt within the dressing effected by passing the same through expressing rollers the material being finally dried by heat. found that the strength of the solution had to be such as to leave within the material after drying a predetermined minimum quantity of the salt which for instance may be equivalent to one seventh of the gross weight of the treated material or dressing, but, of course, such content may be either greater or less than the above figure provided the object of the invention is attained one of which objects is to ensure that in the event that the material or dressing has to be used so that it will become completely saturated bythe As a result of these experiments it was teat Britain July 26, 1932 fluids it absorbs the salt content therein will produce a solution at or above the minimum effective strength. v

To enable the invention to be put into practice one example of a suitable aqueous solution of the salt will now be described also one suitable method of saturating and subsequently expressing the dressings or materials by aid of the accompanying a its equivalent a from whence it flows or is pumped 5 to a pair of sprays b and c by way of the feed pipes at and e respectively. These sprays are arranged in opposing spaced relationship one above and one below the length of material 1 being treated and such material is unwound from a feed roll a and 20 either wound up again on a further roller 71. after treatment, or as is illustrated is fed over such roller h on its way to a heated drying chamber not shown.

The even distribution of the salt through and across the full width of the material being a very essential feature in the process, the saturated material as it leaves the spraysis fed between parallel expressing rollers 12 by means of which it is subjected to an even pressure throughout its length and width sufiicient to express the required amount of moisture and at the same time to evenly distribute the salt residue through and across the material. To obviate undue sagging of the saturated material and to dispense with conveyor bands the sprays are adjustably arranged as close as possible to the point of entry of the material between the expressing rollers for which purpose the sprays may be adjustably mounted.

By setting the expressing rollers so as to leave in the material an equal proportion by weight of the salt solution, there is left, after drying, a quantity of the salt equal to the practical minimum aforementioned, namely, one seventh of the gross weight of the treated material or dressing.

What we claim is:-

1. A medicated dressing containing fiuoborate of sodium (sodium-boro fluoride) in a dry state and in quantity sufilcient to render the dressing sterile and lethal and inhibitory to the growth of micro-organisms therein.

2. a medicated dressing containing in a dried condition a quantity of fiuoborate of sodium (sodium-boro fluoride) equivalent to at least oneseventh of the gross weight of the treated material or dressing. LEON ZISSERMAN.

EDWARD SHORE. 

